Aventia Runes

There are runes available that increase either your melee or magic post 40 by a certain amount. Lesser magic Runes  give a 13% bonus and Greater magic Runes give 25% bonus, and epic magic runes give 50% bonus to your post 40 magic dmg, and duration (e.g. lvl 50 pure wiz gets 1% dmg increas per post 40 lvl so at lvl 50 that's a 10% increase to spell dmg, with a Epic magic rune it would be 15% increase.

Lesser melee runes add .25 to your MF, and greater melee runes add .5, and Epic Melee runes add 1.0 MF to your toon.